| 发明名称 |
METHOD FOR SCREENING ANTICANCER AGENT OR SIP1/ZEB2 INHIBITOR USING INTEGRIN ALPHA 5 |
| 摘要 |
The present invention relates to a method for screening anticancer agent or SIP1/ZEB2 inhibitor using integrin alpha 5 (ITGA5), more precisely a method for measuring integrin alpha 5 expression pattern in SIP1/ZEB2 over-expressing cell line or SIP1/ZEB2 expression induced cell line, both treated with sample compounds, by comparing with that of the control. The method of the present invention facilitates screening of anticancer agent or SIP1/ZEB2 inhibitor simply by measuring integrin alpha 5 expression, so that it can be effectively applied in the field of medicine. |
| 申请公布号 |
US2012201838(A1) |
申请公布日期 |
2012.08.09 |
| 申请号 |
US200813500502 |
申请日期 |
2008.12.05 |
| 申请人 |
KIM SEMI;KANG HEE YOUNG;CHOI MYOUNG SUK;LEE MI-RA;YOO JIN-SAN;PARK YOUNG KYU;KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY |
发明人 |
KIM SEMI;KANG HEE YOUNG;CHOI MYOUNG SUK;LEE MI-RA;YOO JIN-SAN;PARK YOUNG KYU |
| 分类号 |
A61K39/395;A61K31/713;A61P35/00;C12Q1/68;G01N21/64;G01N33/566 |
主分类号 |
A61K39/395 |
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