发明名称 COMPOSITION AND USE OF ET743 FOR TREATING CANCER
摘要 <P>PROBLEM TO BE SOLVED: To provide a use of ET743 in the preparation of a medicament for the treatment of the human body for cancer, a pharmaceutically prescribed medicament including ET743 for intravenous injection for treating human cancer, and a method for treating cancer in a human patient, including administering ET743. <P>SOLUTION: The method includes: administering ET743 in a dose of 1,000 to 1,500 micrograms per 1 m<SP POS="POST">2</SP>of the body surface area over 24 hours by intravenous injection, or administering ET743 in a dose of 1,000 to 1,650 micrograms per 1 m<SP POS="POST">2</SP>of the body surface area over 3 hours by intravenous injection. The method is effective for advanced and/or metastatic previously-treated cancer and cancer resistant or refractory to other treatments, such as sarcoma, particularly, soft tissue sarcoma or bone sarcoma, and mammary cancer. <P>COPYRIGHT: (C)2012,JPO&INPIT
申请公布号 JP2012149095(A) 申请公布日期 2012.08.09
申请号 JP20120105249 申请日期 2012.05.02
申请人 PHARMA MAR SA 发明人 CVITKOVIC ESTEBAN;DEMETRI GEORGE DANIEL;GUZMAN CECILIA;JIMENO JOSE;LOPEZ LAZARO LUIS;MISSET JEAN LOUIS;TWELVES C;VON HOFF DANIEL D
分类号 A61K31/4985;C07D515/22;A61K31/4995;A61K31/573;A61K35/56;A61P35/00;A61P43/00 主分类号 A61K31/4985
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