发明名称 |
PRODUCTION METHOD FOR ADHESIVE PATCH |
摘要 |
<p>The present invention addresses the problem of providing a production method for a compound (A)-containing adhesive patch, said production method being capable of reducing the effect of lactic acid on the physical properties of an adhesive layer and of obtaining an adhesive patch containing 2-(4-ethyl-1-piperazinyl)-4-(4-fluorophenyl)-5,6,7,8,9,10-hexahydro cycloocta[b]pyridine and with excellent physical properties of the adhesive layer. The production method for the adhesive patch is characterized by having: a step (a) in which is formed an adhesive layer which contains a 2-(4-ethyl-1-piperazinyl)-4-(4-fluorophenyl)-5,6,7,8,9,10-hexahydrocycloocta[b]pyridine or a physiologically acceptable acid addition salt thereof, an acrylic polymer, and an organic liquid component compatible with the acrylic polymer, and which does not contain lactic acid; and a step (b) in which lactic acid is caused to be included in the adhesive layer.</p> |
申请公布号 |
WO2012105623(A1) |
申请公布日期 |
2012.08.09 |
申请号 |
WO2012JP52311 |
申请日期 |
2012.02.01 |
申请人 |
NITTO DENKO CORPORATION;DAINIPPON SUMITOMO PHARMA CO., LTD.;OKADA, KATSUHIRO;NISHIMURA, MASATO;KAWAHARADA, YUJI;OKADA, YASUAKI |
发明人 |
OKADA, KATSUHIRO;NISHIMURA, MASATO;KAWAHARADA, YUJI;OKADA, YASUAKI |
分类号 |
A61K31/496;A61K9/70;A61K47/12;A61K47/32;A61P25/18;A61P43/00 |
主分类号 |
A61K31/496 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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