发明名称 A BICARBONATE SALT AND A METHOD OF PREPARING IMATINIB AND SALT USING THE SAME
摘要 PURPOSE: A method for preparing imatinib or salt thereof using novel bicarbonate salt is provided to simply and cheaply obtain the imatinib or salt. CONSTITUTION: A method for preparing imatinib or salt thereof comprises: a step of reacting a compound of chemical formula 1 with cyanamide, bicarbonate, or salt thereof to prepare a compound of chemical formula 2; and a step of reacting a compound of chemical formula 2 with a compound of chemical formula 3. The salt is imatinib mesilate. Bicarbonate salt is denoted by chemical formula 2.
申请公布号 KR20120089039(A) 申请公布日期 2012.08.09
申请号 KR20110010130 申请日期 2011.02.01
申请人 ST PHARM CO., LTD. 发明人 LIM, GEUN GHO;CHANG, SUN KI;WON, SOON KI
分类号 C07D401/04;A61K31/506;C07C279/18 主分类号 C07D401/04
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