METHOD FOR PRODUCING AMINOPHENYL PYRIMIDINYL ALCOHOL DERIVATIVE, AND SYNTHESIS INTERMEDIATE THEREOF

摘要

[Problem] The present invention provides: a method for producing an aminophenyl pyrimidinyl alcohol derivative and a synthesis intermediate thereof, the method being implementable using a simple operation under mild conditions without a special reaction device having to be used. [Solution] The present invention provides: a method for producing an aminophenyl pyrimidinyl alcohol derivative represented by general formula (3) (in the formula, R represents an alkoxymethyl group), and also provides a nitrophenyl pyrimidinyl alcohol derivative represented by formula (2) (in the formula, X represents a hydrogen atom or a halogen atom and R represents the same as above), the method being characterized in that a carbonyl group of a nitrophenyl pyrimidinyl ketone derivative represented by general formula (1) (in the formula, X and R represent the same as above) is reduced to produce the nitrophenyl pyrimidinyl alcohol derivative represented by general formula (2), whereupon the alcohol derivative is reduced.