The invention provides for compounds that are phosphodiesterase inhibitors. The invention further provides for a method for screening compounds that bind to and modulate a phosphosdiesterase protein. The invention also provides methods for treating conditions associated with accumulated amyloid-beta peptide deposit accumulations by administering a phosphodiesterase-binding compound to a subject.
申请公布号
EP2379076(A4)
申请公布日期
2012.08.08
申请号
EP20090835413
申请日期
2009.09.29
申请人
THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
发明人
FENG, YAN;ARANCIO, OTTAVIO;DENG, SHIXIAN;LANDRY, DONALD, W.