发明名称 |
PEPTIDE INHIBITING DIFFERENTIATION OF HEMATOPOIETIC STEM CELLS OR HEMATOPOIETIC PRECURSOR CELLS AND USE OF SAME |
摘要 |
<p>The present invention provides a novel peptide that can be effectively used to produce or grow tissue-specific stem cells or tissue-specific progenitor cells in vitro. The peptide of the invention is a peptide having an amino acid sequence consisting of the amino acid residues set forth in SEQ ID NO:1, or an analog thereof. A feature of the peptide of the invention is having at least one of the following effects: (1) an effect of inhibiting differentiation of hematopoietic stem cells or hematopoietic progenitor cells into myeloid cells, (2) an effect of promoting amplification of mesenchymal stem cells, and (3) an effect of inducing hematopoietic stem cells from pluripotent stem cells.</p> |
申请公布号 |
EP2484689(A1) |
申请公布日期 |
2012.08.08 |
申请号 |
EP20100820615 |
申请日期 |
2010.09.29 |
申请人 |
KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION |
发明人 |
SUGIYAMA, DAISUKE |
分类号 |
C07K7/08;C07K7/06;C07K16/18;C12N5/0789 |
主分类号 |
C07K7/08 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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