发明名称 |
CONCENTRATED AQUEOUS AZALIDE FORMULATIONS |
摘要 |
The present invention relates to formulations of concentrated azalide antibiotics and methods for making and using them. Specifically, the invention relates to a method of treating an infection comprising administering to a patient in need thereof, an effective amount of a concentrated aqueous azalide antibiotic formulation made according to the method comprising dissolving an azalide antibiotic in an aqueous solution comprising a strong acid. The invention also relates to methods for making concentrated aqueous azalide antibiotic formulations for use in pulmonary infection, a nasopharyngeal infection, an otic infection, an ocular infection, a dermal or a vaginal infection. The invention also relates to concentrated aqueous azalide antibiotic formulations made by dissolving an azalide antibiotic in an aqueous solution comprising a strong acid. |
申请公布号 |
EP2211617(A4) |
申请公布日期 |
2012.08.08 |
申请号 |
EP20080796298 |
申请日期 |
2008.07.18 |
申请人 |
INSITE VISION, INC. |
发明人 |
BOWMAN, LYLE, M.;CHANDRASEKARAN, S., KUMAR;ARCHIBALD, ROY, DUANE;PHAM, STEPHEN;MUFSON, DAVID |
分类号 |
A61K31/7052;A61K9/08;A61K31/573;A61K47/10;A61K47/26;A61K47/32;A61K47/38;A61P31/04 |
主分类号 |
A61K31/7052 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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