发明名称 |
TNF superfamily collectin fusion proteins |
摘要 |
The present invention refers to a fusion protein comprising a TNF-superfamily (TNFSF) cytokine or a receptor binding domain thereof fused to a collectin trimerization domain, to a nucleic acid molecule encoding the fusion protein, and to a cell comprising the nucleic acid molecule. The fusion protein is present as a trimeric complex or as an oligomer thereof. The fusion protein, the nucleic acid, and the cell is suitable as pharmaceutical composition or for therapeutic, diagnostic and/or research applications. |
申请公布号 |
EP2484691(A1) |
申请公布日期 |
2012.08.08 |
申请号 |
EP20120166865 |
申请日期 |
2008.07.10 |
申请人 |
APOGENIX GMBH |
发明人 |
HILL, OLIVER;GIFFERS, CHRISTIAN;THIEMANN, MEINOLF;BRANSCHAEDEL, MARCUS |
分类号 |
C07K14/525;A61K38/19;C12N5/10;C12N15/28;C12N15/62 |
主分类号 |
C07K14/525 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|