METHOD FOR IDENTIFYING SUBSTANCE APPLICABLE TO TREATMENT OF NEURODEGENERATIVE DISEASES USING TOLL-LIKE RECEPTOR 2 AS A DRUG TARGET AND KIT USING THE SAME

摘要

PURPOSE: A method for identifying a material having neuropathic disease treatment effect is provided to effectively identify the material using toll-like receptor 2. CONSTITUTION: A method for identifying a material having neuropathic disease treatment effect comprises: a step of contacting a material with toll-like receptor(TLR) 2 and a step of determining the effect of a material to TLR 2. TLR 2 has an amino acid sequence of sequence number 1. An essay for the effect of a material to TLR2 comprises a step of evaluating the reduction of binding between TLR 2 antibody and TLR 2. A kit for identifying the material contains TLR 2 or TLR 2 antibody as an active ingredient.