发明名称 |
SYNTHETIC MYOSTATIN PEPTIDE ANTAGONISTS |
摘要 |
The present invention relates to novel synthetic myostatin antagonists, comprising a synthetic mature myostatin peptide, wherein the peptide comprises at least two cysteine residues at positions 281 and 282 which are forced to bond and form a disulfide bond or a functional variant or fragment thereof and are useful in the treatment of myostatin related disorders. |
申请公布号 |
EP2483300(A1) |
申请公布日期 |
2012.08.08 |
申请号 |
EP20100820883 |
申请日期 |
2010.09.29 |
申请人 |
COVITA LIMITED |
发明人 |
BOWER, ROBERT SYNDECOMBE;MOURA, MONICA SENNA SALERNO DE;NICHOLAS, GINA DIANE;BERRY, CAROLE JUDITH;THOMAS, MARK FRANCIS |
分类号 |
C07K14/475;A61K38/08;A61K38/10;A61K38/18;A61P3/04;A61P3/10;A61P17/00;A61P19/10;A61P21/06;C07K7/06;C07K7/08;C07K14/435;C07K17/08;C12N15/12 |
主分类号 |
C07K14/475 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|