发明名称 Pyrazine derivatives as ENAC blockers
摘要 A compound of Formula I or a hydrate or solvate thereof, where R1, R2, R3, R4, R5, R6, R7, R8, R9, and R10 have the meanings as indicated in the specification, is useful for treating diseases which respond to the blockade of the epithelial sodium channel. Pharmaceutical compositions that contain the compounds and processes for preparing the compounds are also described.
申请公布号 US8236808(B2) 申请公布日期 2012.08.07
申请号 US20090995647 申请日期 2009.06.08
申请人 COLLINGWOOD STEPHEN PAUL;DEVEREUX NICHOLAS JAMES;HOWSHAM CATHERINE;HUNT PETER;HUNT THOMAS ANTHONY;NOVARTIS AG 发明人 COLLINGWOOD STEPHEN PAUL;DEVEREUX NICHOLAS JAMES;HOWSHAM CATHERINE;HUNT PETER;HUNT THOMAS ANTHONY
分类号 A61K31/4965;C07D241/20 主分类号 A61K31/4965
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