发明名称 Method of treating or preventing infertility in a female mammal and pharmaceutical kit for use in such method
摘要 The present invention relates to a method of treating infertility in a female mammal that involves controlled ovarian hyperstimulation. The method includes administering to the female a combination of (i) an FSH substance in an amount effective to stimulate follicular development and (ii) a steroid in an effective amount to inhibit or suppress the secretion of luteinising hormone. The steroid can be substances represented by the following formula in which formula R1, R2, R3, R4 independently are a hydrogen atom, a hydroxyl group or an alkoxy group with 15 carbon atoms; each of R5, R6, R7 is a hydroxyl group; no more than 3 of R1, R2, R3, R4 are hydrogen atoms; derivatives of the aforementioned steroid substances; or mixtures of one or more of the aforementioned substances or derivatives.
申请公布号 US8236785(B2) 申请公布日期 2012.08.07
申请号 US20080522313 申请日期 2008.01.07
申请人 COELINGH BENNINK HERMAN JAN TIJMEN;PANTARHEI BIOSCIENCE B.V. 发明人 COELINGH BENNINK HERMAN JAN TIJMEN
分类号 A01N45/00;A61K31/56 主分类号 A01N45/00
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