发明名称 |
Modified flagellin improved toll-like receptor 5 stimulating activity |
摘要 |
Disclosed herein are flagellin mutants having an enhanced activity of stimulating the toll-like receptor-5 (hereinafter referred to as “TLR5”). More specifically, disclosed are flagellin mutants, prepared by point-mutating some of the amino acids of a TRL5 agonist flagellin so as to enhance the TRL-stimulating activity of the flagellin. |
申请公布号 |
US8236327(B2) |
申请公布日期 |
2012.08.07 |
申请号 |
US20080526187 |
申请日期 |
2008.02.05 |
申请人 |
RHEE JOON HAENG;LEE SHEE EUN;KIM SOO YOUNG;INDUSTRY FOUNDATION OF CHONNAM NATIONAL UNIVERSITY |
发明人 |
RHEE JOON HAENG;LEE SHEE EUN;KIM SOO YOUNG |
分类号 |
A61K39/106 |
主分类号 |
A61K39/106 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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