发明名称 |
Substituted 1,2,3-triazolopyrimidines for the inhibition of NAD(P)H oxidases and platelet activation |
摘要 |
The invention relates to compounds of formula het-X-AB containing a N-heteroaryl moiety “het”, which is linked via X=sulfur to the 1,2,3-triazolo[4,5-d]pyrimidine-7-yl moiety AB of the formula (II). The invention also relates to a process for the preparation of said compounds and the use thereof in drugs for the treatment of NAD(P)H oxidase-related diseases and disorders and inhibition of platelet activation. |
申请公布号 |
US8236809(B2) |
申请公布日期 |
2012.08.07 |
申请号 |
US20050579999 |
申请日期 |
2005.05.13 |
申请人 |
TEGTMEIER FRANK;WALTER ULRICH;SCHINZEL REINHARD;WINGLER KIRSTIN;SCHEURER PETER;SCHMIDT HARALD;VASOPHARM GMBH |
发明人 |
TEGTMEIER FRANK;WALTER ULRICH;SCHINZEL REINHARD;WINGLER KIRSTIN;SCHEURER PETER;SCHMIDT HARALD |
分类号 |
C07D487/04;A61K31/519;A61P9/00;A61P13/12;A61P19/02;A61P25/28;A61P35/00 |
主分类号 |
C07D487/04 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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