发明名称 Pharmaceutical composition of solifenacin or salt thereof for use in solid formulation and use of substance with ethylene oxide chain
摘要 A pharmaceutical composition of solifenacin or salt thereof, which is stable and inhibited from decomposition with time for use in solid pharmaceutical preparation, comprising crystalline and amorphous solifenacin or a crystalline and amorphous salt thereof, whereby amorphous content is 77 % or less, together with an amorphization inhibitor. A substance having ethylene oxide chain, such as polyethylene glycol, is used as amorphization inhibitor.
申请公布号 SK6199(Y1) 申请公布日期 2012.08.06
申请号 SK20110005020U 申请日期 2005.03.24
申请人 ASTELLAS PHARMA INC. 发明人 SUGIHARA AKIO;YASUJI TAKEHIKO;MASAKI KATSUHIRO;MURAYAMA DAISUKE
分类号 A61K31/439;A61K9/20;A61K47/34;A61P1/12;A61P13/02;A61P27/08;C07D453/02 主分类号 A61K31/439
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