The present invention provides assay systems and related methods for determining genetic abnormalities in mixed samples comprising cell free DNA from both normal and putative genetically atypical cells. Exemplary mixed samples for analysis using the assay systems of the invention include samples comprising both maternal and fetal cell free DNA and samples that contain DNA from normal cells and circulating cancerous cells.
申请公布号
WO2012103031(A2)
申请公布日期
2012.08.02
申请号
WO2012US22261
申请日期
2012.01.23
申请人
ARIOSA DIAGNOSTICS, INC.;OLIPHANT, ARNOLD;SPARKS, ANDREW;SONG, KEN;STUELPNAGEL, JOHN
发明人
OLIPHANT, ARNOLD;SPARKS, ANDREW;SONG, KEN;STUELPNAGEL, JOHN