ZWITTERIONIC HYDROPHILIC CHROMATOGRAPHY STATIONARY PHASE AND MANUFACTURING METHOD THEREOF

摘要

A liquid chromatography stationary phase and manufacturing method thereof, the bonding terminal of said chromatography stationary phase is zwitterionic functional group, and said manufacturing method includes the following steps, alkenyl or alkynyl silicone is prepared via horizontal polymerization of alkenyl or slkynyl silicane on the silicone surface, then a thiol click reaction with thiol group containing zwitterionic compound is carried out to obtain the zwitterionic hydrophilic chromagraphy stationary phase. Said stationary phase has zwitterionic characteristic and good hydrophilicity, which is widely used in separation of all kinds of samples.