<p>This invention relates to 5-alkynyl-pyridine of general formula (I) their use as inhibitors of the activity of PI3Kalpha, pharmaceutical compositions containing them, and their use as a medicaments for the treatment and/or prevention of diseases characterized by excessive or abnormal cell proliferation and associated conditions such as cancer. The groups R1 to R6 and n have the meanings given in the claims and in the specification.</p>
申请公布号
WO2012101184(A1)
申请公布日期
2012.08.02
申请号
WO2012EP51165
申请日期
2012.01.25
申请人
BOEHRINGER INGELHEIM INTERNATIONAL GMBH;WUNBERG, TOBIAS;VEEN, VAN DER, LARS;KRAEMER, OLIVER
发明人
WUNBERG, TOBIAS;VEEN, VAN DER, LARS;KRAEMER, OLIVER