发明名称 COMBINATION THERAPY AND CANCER
摘要 The disclosure relates to methods of treating tuberous sclerosis in a subject, comprising administering a composition comprising an mTOR inhibitor and a tyrosine kinase inhibitor to a subject that is diagnosed with, suspected of, or exhibiting symptoms of cancer. In some embodiments, the cancer is tuberous sclerosis. In some embodiments, the mTOR inhibitor is sirolimus and the tyrosine kinase inhibitor is imatinib. In some embodiments, the disclosure relates to a composition comprising an mTOR inhibitor and a tyrosine kinase inhibitor. In some embodiments, the disclosure relates to a composition comprising sirolimus and imatinib.
申请公布号 US2012196870(A1) 申请公布日期 2012.08.02
申请号 US201213357920 申请日期 2012.01.25
申请人 ARBISER JACK L.;EMORY UNIVERSITY 发明人 ARBISER JACK L.
分类号 A61K31/497;A61K31/439;A61P31/00;A61P31/12;A61P35/00 主分类号 A61K31/497
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