摘要 |
<p>The present invention provides a compound of formula (I): and pharmaceutically acceptable salts, enantiomers, stereoisomers, rotamers, tautomers, diastereomers, or racemates thereof. These compounds inhibit the activity of CDK9 and are thus useful as pharmaceuticals. Also provided are methods of treating a disease or condition mediated by CDK9 using the compounds of Formula I and isomers thereof, and pharmaceutical compositions comprising such compounds.</p> |
申请人 |
NOVARTIS AG;ANTONIOS-MCCREA, WILLIAM R.;BARSANTI, PAUL A.;HU, CHENG;JIN, XIANMING;LIN, XIAODONG;MARTIN, ERIC J.;PAN, YUE;PFISTER, KEITH B.;RENHOWE, PAUL A.;SENDZIK, MARTIN;SUTTON, JAMES;WAN, LIFENG |
发明人 |
ANTONIOS-MCCREA, WILLIAM R.;BARSANTI, PAUL A.;HU, CHENG;JIN, XIANMING;LIN, XIAODONG;MARTIN, ERIC J.;PAN, YUE;PFISTER, KEITH B.;RENHOWE, PAUL A.;SENDZIK, MARTIN;SUTTON, JAMES;WAN, LIFENG |