发明名称 |
Modulation of Synaptic Maintenance |
摘要 |
C1q is shown to be expressed in neurons, where it acts as a signal for synapse elimination. Methods are provided for protecting or treating an individual suffering from adverse effects of synapse loss. These findings have broad implications for a variety of clinical conditions, including Alzheimer's disease. |
申请公布号 |
US2012195880(A1) |
申请公布日期 |
2012.08.02 |
申请号 |
US201113326180 |
申请日期 |
2011.12.14 |
申请人 |
BARRES BEN A.;STEVENS BETH A. |
发明人 |
BARRES BEN A.;STEVENS BETH A. |
分类号 |
A61K39/395;A61P25/00;A61P25/28;C12Q1/68;G01N33/566;G01N33/567 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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