| 发明名称 |
ONCE-A-DAY DOSAGE FORM OF TROSPIUM |
| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide a pharmaceutical composition allowing a once-a-day dosage form of trospium. <P>SOLUTION: A pharmaceutical composition of a pharmaceutically acceptable trospium chloride generating an average steady state blood level of trospium with a minimum (C<SB POS="POST">min</SB>) and maximum (C<SB POS="POST">max</SB>) blood levels of about 0.5-2.5 ng/ml and about 2.0-6.0 ng/ml, respectively by administering to a human patient. <P>COPYRIGHT: (C)2012,JPO&INPIT |
| 申请公布号 |
JP2012144577(A) |
申请公布日期 |
2012.08.02 |
| 申请号 |
JP20120104795 |
申请日期 |
2012.05.01 |
| 申请人 |
SUPERNUS PHARMACEUTICALS INC |
发明人 |
KIDANE ARGAW;FLANNER HENRY H;BHATT PADMANABH;RAOUFINIA ARASH |
| 分类号 |
A61K31/46;A61K9/08;A61K9/10;A61K9/14;A61K9/16;A61K9/20;A61K9/22;A61K9/28;A61K9/48;A61K9/50;A61K31/44;A61K31/4747;A61P13/02 |
主分类号 |
A61K31/46 |
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