发明名称 |
METHODS OF DIAGNOSING AND MONITORING REJECTION MEDIATED BY ANTIBODIES |
摘要 |
An intracellular cytokine flow cytometry (CFC) assay was developed to measure CD3− (non-T) cell response to allo-Ags expressed on peripheral blood mononuclear cells (allo-CFC-PBMC) and/or endothelial cells (allo-CFC-EC) by detecting intracellular gamma-interferon (IFNY) production. The assay can be used to determine a likelihood of antibody mediated rejection in an individual. A method for using genetic screening to determine the likelihood of AMR is also disclosed. |
申请公布号 |
US2012192878(A1) |
申请公布日期 |
2012.08.02 |
申请号 |
US201013501434 |
申请日期 |
2010.10.13 |
申请人 |
CEDARS-SINAI MEDICAL CENTER |
发明人 |
TOYODA MIEKO |
分类号 |
C12Q1/68;A61B17/00;C40B30/04;G01N33/566 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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