发明名称 |
Optical Projection Tomography Microscopy (OPTM) for Large Specimen Sizes |
摘要 |
Claimed is an imaging and diagnostic system and method for focal scanning of a specimen using optical projection tomographic microscopy and computer generation of three-dimensional images. One embodiment comprises a light source and an imaging system having an adjustable focal position which acquires a plurality of digital 2D projection images of biological tissue placed within a specimen tube that translates and rotates past an optical lens in a helical pattern. A computer captures the images and generates a 3D composite image. Also claimed is a system and method for preparing a specimen for optical microscopy. One embodiment comprises fixing, staining, and/or optically clearing biological tissue within a microfluidic specimen chamber prior to placement in a specimen tube. |
申请公布号 |
US2012196320(A1) |
申请公布日期 |
2012.08.02 |
申请号 |
US201113091088 |
申请日期 |
2011.04.20 |
申请人 |
SEIBEL ERIC J.;MIAO QIN;COE RYAN LEE;REINHALL PER G.;STORTI DUANE W. |
发明人 |
SEIBEL ERIC J.;MIAO QIN;COE RYAN LEE;REINHALL PER G.;STORTI DUANE W. |
分类号 |
G01N1/30;G01N1/31;H04N7/18;H04N13/02 |
主分类号 |
G01N1/30 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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