发明名称 |
Large-scale production of soluble hyaluronidase |
摘要 |
Provided are methods for preparing culture medium that contains soluble hyaluronidases. The methods employ cells that contain a plurality of active copies of nucleic acid encoding the soluble hyaluronidase and a plurality of feedings and temperature changes, whereby the encoded soluble hyaluronidase is secreted into the cell culture medium. |
申请公布号 |
US2012196348(A1) |
申请公布日期 |
2012.08.02 |
申请号 |
US201213385919 |
申请日期 |
2012.03.13 |
申请人 |
BAKER DAVID;BOOKBINDER LOUIS H. |
发明人 |
BAKER DAVID;BOOKBINDER LOUIS H. |
分类号 |
C12N9/26 |
主分类号 |
C12N9/26 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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