| 发明名称 |
MMP-14 specific cleavage sequence |
| 摘要 |
The present invention relates to compounds, and pharmaceutically acceptable salts thereof, comprising a vascular disrupting agent (VDA) associated and a MMP proteolytic cleavage site. The compounds are useful in the treatment of cancer. |
| 申请公布号 |
EP2481429(A2) |
申请公布日期 |
2012.08.01 |
| 申请号 |
EP20120160565 |
申请日期 |
2008.03.27 |
| 申请人 |
UNIVERSITY OF BRADFORD |
发明人 |
GILL, JASON;LOADMAN, PAUL;FALCONER, ROBERT;PATTERSON, LAURENCE;ATKINSON, JENNIFER;BIBBY, MICHAEL |
| 分类号 |
A61K47/48;A61P9/08;A61P29/02;A61P35/00;C07K7/06 |
主分类号 |
A61K47/48 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
