Biocatalytic processes for the preparation of substantially stereomerically pure fused bicyclic proline compounds
摘要
The present disclosure provides substantially stereomerically pure fused bicyclic proline compounds of structural Formulae II to VII as described herein, and to biocatalytic processes for their preparation, and to the enzymes used in those processes.
申请公布号
EP2481737(A1)
申请公布日期
2012.08.01
申请号
EP20120157520
申请日期
2009.06.23
申请人
MERCK SHARP & DOHME CORP.
发明人
MIJTS, BENJAMIN;COLBECK, JEFFREY;MUNGER, JOHN D., JR.;MAVINAHALLI, JAGADEESH;SHELDON, ROGER;MULEY, SHEELA;LIANG, JACK;NEWMAN, LISA M.;ZHANG, XIYUN;LALONDE, JAMES;CLAY, MICHAEL D.;ZHU, JUN;GRUBER, JOHN M.