发明名称 TREATMENT OF FILAGGRIN (FLG) RELATED DISEASES BY MODULATION OF FLG EXPRESSION AND ACTIVITY
摘要 The present invention relates to antisense oligonucleotides and/or compounds that modulate the expression of and/or function of Filaggrin (FLG), in particular, by targeting natural antisense polynucleotides of Filaggrin (FLG). The invention also relates to the identification of these antisense oligonucleotides and/or compounds and their use in treating diseases and disorders associated with the expression of FLG.
申请公布号 EP2480669(A2) 申请公布日期 2012.08.01
申请号 EP20100819521 申请日期 2010.09.24
申请人 OPKO CURNA, LLC 发明人 COLLARD, JOSEPH;KHORKOVA SHERMAN, OLGA;COITO, CARLOS
分类号 C12N15/113;A61K31/7088;A61K31/713;A61K45/06;A61K48/00;C12N15/63 主分类号 C12N15/113
代理机构 代理人
主权项
地址