发明名称 |
2'-FLUORO-6'-METHYLENE CARBOCYCLIC NUCLEOSIDES AND METHODS OF TREATING VIRAL INFECTIONS. |
摘要 |
<p>The present invention relates to 2'-Fluoro-6'-methylene carbocyclic nucleosides, pharmaceutical compositions containing these nucleosides and their use in the treatment or prophylaxis of a number of viral infections and secondary disease states and conditions thereof, especially including Hepatitis B virus (HBV) and secondary disease states and conditions thereof (cirrhosis and liver cancer), Heptatitis C virus (HCV), Herpes Simplex virus I and II (HSV-1 and HSV-2), cytomegalovirus (CMV), Varicella-Zoster Virus (VZV) and Epstein Barr virus (EBV) and secondary cancers which occur thereof (lymphoma, nasopharyngeal cancer, including drug resistant (especially including lamivudine and/or adefovir resistant) and other mutant forms of these viruses.</p> |
申请公布号 |
MX2012005601(A) |
申请公布日期 |
2012.08.01 |
申请号 |
MX20120005601 |
申请日期 |
2010.11.16 |
申请人 |
UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC.* |
发明人 |
CHU, CHUNG, K.;WANG, JIANING |
分类号 |
C07H19/06;A61K31/7064;A61K31/7076;A61P31/20;C07H19/16 |
主分类号 |
C07H19/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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