发明名称 |
NEW SALTS OF PERINDOPRIL WITH BENZATHINE, PROCESS FOR THEIR PREPARATION AND THEIR USE FOR THE TREATMENT OF CARDIOVASCULAR DISEASES |
摘要 |
The present invention describes new salts of ACE inhibitors with N5N'-dibenzylethylenediamine (abbr.: benzathine salts), a process for their preparation in crystal and amorphous forms by the reaction of two moles of ACE inhibitors with one mole of N,N'-dibenzylethylenediamine, a process for the preparation of pharmaceutical formulations containing these salts and their use for the treatment of cardiovascular diseases. |
申请公布号 |
EP2480231(A2) |
申请公布日期 |
2012.08.01 |
申请号 |
EP20100779347 |
申请日期 |
2010.09.17 |
申请人 |
SILVERSTONE PHARMA |
发明人 |
RUCMAN, RUDOLF;ZUPET, PAVEL |
分类号 |
A61K31/401;A61K31/403;A61K31/551;A61K31/675;A61K45/06;A61P9/00;A61P9/10;A61P9/12;C07D207/16;C07D209/42;C07D487/04 |
主分类号 |
A61K31/401 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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