发明名称 NEW SALTS OF PERINDOPRIL WITH BENZATHINE, PROCESS FOR THEIR PREPARATION AND THEIR USE FOR THE TREATMENT OF CARDIOVASCULAR DISEASES
摘要 The present invention describes new salts of ACE inhibitors with N5N'-dibenzylethylenediamine (abbr.: benzathine salts), a process for their preparation in crystal and amorphous forms by the reaction of two moles of ACE inhibitors with one mole of N,N'-dibenzylethylenediamine, a process for the preparation of pharmaceutical formulations containing these salts and their use for the treatment of cardiovascular diseases.
申请公布号 EP2480231(A2) 申请公布日期 2012.08.01
申请号 EP20100779347 申请日期 2010.09.17
申请人 SILVERSTONE PHARMA 发明人 RUCMAN, RUDOLF;ZUPET, PAVEL
分类号 A61K31/401;A61K31/403;A61K31/551;A61K31/675;A61K45/06;A61P9/00;A61P9/10;A61P9/12;C07D207/16;C07D209/42;C07D487/04 主分类号 A61K31/401
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