发明名称 NOVEL INHIBITORS OF GLUTAMINYL CYCLASE
摘要 The present invention relates to compounds of formula (I), combinations and uses thereof for disease therapy, wherein R1 represents heteroaryl, -carbocyclyl-heteroaryl, -alkenylheteroaryl or -alkylheteroaryl; R2 represents alkyl; carbocyclyl which may optionally be substituted by alkyl; alkenyl; alkynyl, provided a triple bond is not adjacent to X; -alkyl-aryl; -alkyl-heteroaryl; -alkyl-heterocyclyl in which heterocyclyl may optionally be substituted by alkyl; -alkyl-carbocyclyl in which carbocyclyl may optionally be substituted by alkyl; aryl; heteroaryl; or H; X represents S or NR3; R3 represents H or C1-4 alkyl.
申请公布号 SI2091948(T1) 申请公布日期 2012.07.31
申请号 SI20070030921T 申请日期 2007.11.28
申请人 PROBIODRUG AG 发明人 BUCHHOLZ MIRKO;NIESTROJ ANDRE J.;HEISER ULRICH;RAMSBECK DANIEL;SCHILLING STEPHAN
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