| 摘要 |
39PARENTERAL PHARMACEUTICAL FORMULATION IN SUSPENSION,HAVING SUSTAINED RELEASE, IN LOW AND ULTRALOW DOSAGE, INHORMONAL THERAPY IN THE CLIMACTERIC SYNDROMEParenteral pharmaceutical formulation or composition, in suspension, having sustained release, containing suspended particles of estradiol and progesterone for hormonal replacement in female mammals in low and ultralow dosage; the formulation consists of an10 injectable suspension comprising particles of estradiol, particles of progesterone, a surfactant agent, an isosmotic agent, a thickening agent, and one or more preservation agents, wherein the estradiol is in particles having a size between 1 and 100 microns and the progesterone is in particles having a size between 1 and 100 microns, for application thereof in parenteral, intramuscular, subcutaneous or intradermal pharmaceutical form.15Figure 1 |
