| 发明名称 |
METHOD OF PREDICTING RISK OF IDIOPATHIC SCOLIOSIS DEVELOPMENT IN CHILDREN |
| 摘要 |
FIELD: medicine. ^ SUBSTANCE: invention relates to field of medicine, namely to orthopedics and medical genetics. In order to predict risk of idiopathic scoliosis development in children polymorphism of transforming growth factor 1 gene C-509T is isolated from patients' peripheral venous blood. In case of detection of -509TT genotype, higher risk of idiopathic scoliosis development is predicted. If genotypes -509CT and -509CC are identified, absence of risk of idiopathic scoliosis development in children is predicted. ^ EFFECT: method makes it possible to predict risk of idiopathic scoliosis development in children on the basis of identification of polymorphism of transforming growth factor 1 gene C-509T. ^ 1 tbl |
| 申请公布号 |
RU2456925(C1) |
申请公布日期 |
2012.07.27 |
| 申请号 |
RU20110109776 |
申请日期 |
2011.03.15 |
| 申请人 |
GOSUDARSTVENNOE OBRAZOVATEL'NOE UCHREZHDENIE VYSSHEGO PROFESSIONAL'NOGO OBRAZOVANIJA "KURSKIJ GOSUDARSTVENNYJ MEDITSINSKIJ UNIVERSITET MINISTERSTVA ZDRAVOOKHRANENIJA I SOTSIAL'NOGO RAZVITIJA ROSSIJSKOJ FEDERATSII" |
发明人 |
POLONIKOV ALEKSEJ VALER'EVICH;RYZHKOV IGOR' IVANOVICH;SOLODILOVA MARIJA ANDREEVNA;CHURNOSOV MIKHAIL IVANOVICH;IVANOVA NATAL'JA VASIL'EVNA;DEDKOV ANDREJ ANATOL'EVICH;BORZILOV EVGENIJ EVGEN'EVICH |
| 分类号 |
A61B10/00;G01N33/48 |
主分类号 |
A61B10/00 |
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