| 摘要 |
<p>Disclosed are Uracil or Thymine derivatives of formula (I) examples of which are: (E)-N-(4-(3-tert-butyl-5-(2,4-dioxotetrahydropyrimidin-1(2H)-yl)-2-methoxystyryl)phenyl)methanesulfonamide; (E)-N-(4-(3-tert-butyl-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-2-methoxystyryl)phenyl)methanesulfonamide (Z)-N-(4-(2-(3-tert-butyl-5-(2,4-dioxotetrahydropyrimidin-1(2H)-yl)-2-methoxyphenyl)-1-chlorovinyl)phenyl)methanesulfonamide; (E)-1-(3-tert-butyl-5-(4-fluorostyryl)-4-methoxyphenyl) dihydropyrimidine-2,4(1H,3H)-dione; The compounds are for use in treating Hepatitis C</p> |
| 申请人 |
ABBOTT LABORATORIES |
发明人 |
FRANCZYK, THADDEUS S;WAGNER, ROLF;TUFANO, MICHAEL D;STEWART, KENT D;ROCKWAY, TODD W;RANDOLPH, JOHN T;PRATT, JOHN K;MOTTER, CHRISTOPHER E;MARING, CLARENCE J;LONGENECKER, KENTON L;LIU, YAYA;LIU, DACHUN;KRUEGER, ALLAN C;KATI, WARREN M;HUTCHINSON, DOUGLAS K;HUANG, PEGGY P;FLENTGE, CHARLES A;DONNER, PAMELA L;DEGOEY, DAVID A;BETEBENNER, DAVID A;BARNES, DAVID M;CHEN, SHUANG;GAO, YI;HAIGHT, ANTHONY R;HENGEVELD, JOHN E;HENRY, RODGER F;KOTECKI, BRIAN J;LOU, XIAOCHUN;SARRIS, KATHY;ZHANG, GEOFF G |
