| 摘要 |
Disclosed is a process for preparing an oral, solid fast dispersing dosage form of a pharmaceutically active substance, wherein said substance exhibits polymorphism in an aqueous environment, comprising the steps of: (a) forming a suspension of particles of said substance in a carrier material in a continuous phase, wherein the carrier material comprises standard molecular weight fish gelatin; (b) reducing the suspension temperature to less than about 15ºC; (c) forming discrete units of the suspension at a formation temperature of less than about 15ºC; and (d) removing the continuous phase to leave the suspension of particles in the carrier material. |
