| 发明名称 |
ANTI-CD19 ANTIBODY AND USE IN ONCOLOGY |
| 摘要 |
<P>PROBLEM TO BE SOLVED: To provide immunotherapeutic compositions for B cell diseases and disorders in human subjects, and methods for the treatment using therapeutic antibodies that bind to a human CD 19 antigen. <P>SOLUTION: The present invention relates to pharmaceutical compositions comprising human or humanized anti-CD 19 antibodies of the IgGl or IgG3 human isotype. The present invention relates to pharmaceutical compositions comprising human or humanized anti-CD 19 antibodies of the IgG2 or IgG4 human isotype that preferably mediate human ADCC. <P>COPYRIGHT: (C)2012,JPO&INPIT |
| 申请公布号 |
JP2012140446(A) |
申请公布日期 |
2012.07.26 |
| 申请号 |
JP20120039043 |
申请日期 |
2012.02.24 |
| 申请人 |
DUKE UNIV |
发明人 |
TEDDER THOMAS F;HAMAGUCHI YASUHITO;GRON HANNE;YAZAWA NORIHITO |
| 分类号 |
A61K39/395;A61P35/02;C07K16/30;C12N15/09;C12P21/08 |
主分类号 |
A61K39/395 |
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