| 摘要 |
A solution packaging system (10) is disclosed. One embodiment of the solution packaging system of the present invention comprises a gas-impermeable dual-chamber bag (15) , having a first chamber (30) and a second chamber (35) separated by a frangible (releasable) seal (25) , and an over-wrap member (20) enclosing and containing the dual-chamber inner bag. The dual-chamber bag can be used to package two-part medicinal solutions containing bicarbonate, such as ophthalmic irrigation solutions. The over-wrap member can serve as a dust cover and need not be a moisture or gas barrier, as the dual-chamber inner bag will have sufficient gas barrier properties to minimize the loss of CO2 from the first part of the solution (, the bicarbonate) . The dual-chamber bag can be fitted with an administration port (110) , and sealed with a stopper and an aluminum crimp seal. The dual-chamber bag can further comprise fill-ports (100) to fill each chamber. The fill port openings can be sealed after filling the chambers and the fill ports cut from the dual-chamber bag. The frangible seal between the chambers of the embodiments of this invention can be broken by the end user to mix and reconstitute the two parts of the solution prior to use. |
