METHOD FOR PRODUCING FLUOROAMINE

摘要

A fluoroamine can be produced by: protecting an amino group of an amino alcohol with a nitrobenzenesulfonyl group, thereby converting into a protected amino alcohol (amino group protection step); causing the protected amino alcohol to react with sulfuryl fluoride (SO2F2) in the presence of an organic base, thereby converting into a protected fluoroamine (dehydroxyfluorination step); and eliminating the protective group of the amino group of the protected fluoroamine (deprotection step). Since a nitrobenzenesulfonyl group highly satisfies the conditions required for the protective group of an amino group of the present invention, an aimed fluoroamine can be obtained with high purity and high yield.