| 发明名称 |
INHIBITORS OF PHOSPHATIDYLINOSITOL-3-KINASE (PI3) AND INDUCERS OF NITRIC OXIDE (NO) |
| 摘要 |
The present invention relates to compounds of general formula I for the treatment of malignancy by inhibition of PI3-Akt pathway and or induction of NO. The present invention also relates to the use of compound of general formula I for the treatment of malignancy by inhibition of PI3-Akt pathway and or induction of NO. The present invention further relates to a method of treating malignancy by inhibition of PI3-Akt pathway and or induction of NO by administration of compound or said composition to a mammal in need thereof.
|
| 申请公布号 |
US2012190738(A1) |
申请公布日期 |
2012.07.26 |
| 申请号 |
US201013144263 |
申请日期 |
2010.01.12 |
| 申请人 |
BANDYOPADHYAY SANTU;PAL BIKAS CHANDRA;PARASURAMAN JAISANKAR;ROY SIDDHARTHA;CHAKRABOTRY JAYASHREE BAGCHI;MUKHERJEE INDRANI CHOUDHURY;MAHATO SANJIT KUMAR;KONAR ADITYA;RAKSHIT SRABANTI;MANDAL LABANYA;GANGULY DIPYAMAN;PAUL KAUSIK;MANNA ANIRBAN;VINAYAGAM JAYARAMAN;PAL CHURALA |
发明人 |
BANDYOPADHYAY SANTU;PAL BIKAS CHANDRA;PARASURAMAN JAISANKAR;ROY SIDDHARTHA;CHAKRABOTRY JAYASHREE BAGCHI;MUKHERJEE INDRANI CHOUDHURY;MAHATO SANJIT KUMAR;KONAR ADITYA;RAKSHIT SRABANTI;MANDAL LABANYA;GANGULY DIPYAMAN;PAUL KAUSIK;MANNA ANIRBAN;VINAYAGAM JAYARAMAN;PAL CHURALA |
| 分类号 |
A61K31/36;A61K31/05;A61K31/138;A61K31/15;A61K31/225;A61K31/277;A61P35/00;A61P35/02;C07C39/10;C07C69/353;C07C215/54;C07C255/33;C07D317/50 |
主分类号 |
A61K31/36 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
