发明名称 TUBERCULOSIS MUTANTS
摘要 The present invention relates to mycobacterial genes involved in phagosome maturation arrest. In another aspect, the present invention relates to assays for identifying virulence genes in intracellular pathogens and for identifying agents against intracellular pathogens. In a further aspect, the present invention relates to Mycobacterium tuberculosis mutants and their use as a vaccine. In a further aspect, the present invention relates to a vaccine for tuberculosis and methods of its production.
申请公布号 WO2012031752(A3) 申请公布日期 2012.07.26
申请号 WO2011EP04504 申请日期 2011.09.07
申请人 INSTITUT PASTEUR KOREA;CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS);INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (EPST);UNIVERSITE TOULOUSE III - PAUL SABATIER;BRODIN, PRISCILLE;PARK, SEJIN;EWANN, FANNY ANNE;PEGUILLET, ISABELLE;FENISTEIN, DENIS;CHRISTOPHE, THIERRY;GENOVESIO, AUGUSTE;NEYROLLES, OLIVIER;LEVILLAIN, FLORENCE;GICQUEL, BRIGITTE;POCQUET, YANNICK 发明人 BRODIN, PRISCILLE;PARK, SEJIN;EWANN, FANNY ANNE;PEGUILLET, ISABELLE;FENISTEIN, DENIS;CHRISTOPHE, THIERRY;GENOVESIO, AUGUSTE;NEYROLLES, OLIVIER;LEVILLAIN, FLORENCE;GICQUEL, BRIGITTE;POCQUET, YANNICK
分类号 A61K39/04;C12Q1/68;G01N33/52 主分类号 A61K39/04
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