发明名称 BIOMARKERS FOR RAPID DETERMINATION OF DRUG EFFICACY
摘要 The invention provides compositions and methods for determining GLP-1 analog and/or DPPIV inhibitor response in a subject. In one embodiment, the composition comprises a solid support comprising probes for measuring a biomarker panel comprising, for example, adiponectin, C-peptide, hsCRP, insulin, proinsulin. The simultaneous use of multiple biomarkers with independent classification power will increase the performance of the biomarker panel in characterizing GLP-1 analog and DPPIV inhibitor response. The invention also provides methods of treating a subject (e.g. one experiencing cardiodiabetes) and determining the efficacy of a therapy through assaying the various biomarkers of a biomarker panel disclosed herein.
申请公布号 CA2825709(A1) 申请公布日期 2012.07.26
申请号 CA20122825709 申请日期 2012.01.23
申请人 IR2DX, INC. 发明人 PFUETZNER, ANDREAS
分类号 G01N33/74;G01N33/68 主分类号 G01N33/74
代理机构 代理人
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