METHOD OF MANUFACTURING STABLE AND HIGH CONCENTRATION CALCIUM PHOSPHATE AQUEOUS SOLUTIONS IN NEUTRAL PH RANGE

摘要

PURPOSE: A producing method of high concentration calcium phosphate aqueous solution is provided to obtain a calcium phosphate solution stable in the neutral condition for preventing the re-extraction. CONSTITUTION: A producing method of high concentration calcium phosphate aqueous solution comprises the following steps: preparing an acid solution using an acid chelating agent; dissolving a calcium phosphate compound in the acid solution to obtain a calcium phosphate aqueous solution; and adding a pH adjusting agent and phosphoric acid into the calcium phosphate aqueous solution. The acid chelating agent is either citric acid or EDTA(ethylene diamine tetra-acetic acid). The calcium phosphate compound is selected from the group consisting of hydroxyapatite, carbonated apatite, tricalcium phosphate, and calcium hydrogen phosphate. The pH of the calcium phosphate aqueous solution is 5.5-6.1.