发明名称 GLYCINE COMPOUND
摘要 [Problem] The present invention provides a compound which is useful as an active ingredient of a pharmaceutical composition, in particular, a pharmaceutical composition for preventing and/or treating VAP-1-related diseases. [Means for Solution] The present inventors have conducted intensive studies on a compound having a VAP-1 inhibitory activity, and as a result, they have found that a compound of the present invention or a salt thereof exhibits an excellent VAP-1 inhibitory activity and is useful for preventing and/or treating VAP-1-related diseases, in particular, diabetic nephropathy or diabetic macular edema, thereby completing the present invention. The present invention further relates to a pharmaceutical composition, in particular, a pharmaceutical composition for preventing and/or treating VAP-1-related diseases, which comprises the compound of the present invention or a salt thereof, and an excipient.
申请公布号 EP2479165(A1) 申请公布日期 2012.07.25
申请号 EP20100817191 申请日期 2010.09.15
申请人 ASTELLAS PHARMA INC. 发明人 YOSHIHARA, KOUSEI;SUZUKI, DAISUKE;YAMAKI, SUSUMU;KOGA, YUJI;SEKI, NORIO;FUJIYASU, JIRO;NEYA, MASAHIRO
分类号 C07C237/04;A61K31/165;A61K31/166;A61K31/167;A61K31/17;A61K31/18;A61K31/216;A61K31/27;A61K31/277;A61K31/351;A61K31/357;A61K31/40;A61K31/4035;A61K31/4402;A61K31/4406;A61K31/4418;A61K31/4439;A61K31/451;A61K31/454;A61K31/4545;A61K31/472 主分类号 C07C237/04
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