摘要 |
[Problem] The present invention provides a compound which is useful as an active ingredient of a pharmaceutical composition, in particular, a pharmaceutical composition for preventing and/or treating VAP-1-related diseases. [Means for Solution] The present inventors have conducted intensive studies on a compound having a VAP-1 inhibitory activity, and as a result, they have found that a compound of the present invention or a salt thereof exhibits an excellent VAP-1 inhibitory activity and is useful for preventing and/or treating VAP-1-related diseases, in particular, diabetic nephropathy or diabetic macular edema, thereby completing the present invention. The present invention further relates to a pharmaceutical composition, in particular, a pharmaceutical composition for preventing and/or treating VAP-1-related diseases, which comprises the compound of the present invention or a salt thereof, and an excipient. |
申请人 |
ASTELLAS PHARMA INC. |
发明人 |
YOSHIHARA, KOUSEI;SUZUKI, DAISUKE;YAMAKI, SUSUMU;KOGA, YUJI;SEKI, NORIO;FUJIYASU, JIRO;NEYA, MASAHIRO |