发明名称 |
CyaA-carried polypeptide(s) and use to induce both therapeutic and prophylactic immune responses |
摘要 |
The invention is directed to means, based on CyaA-carried polypeptide(s), for use in the immunotherapeutic treatment of first determined pathological condition(s) diagnosed in a mammalian host by eliciting a T cell immune response against a first group of epitopes contained in said polypeptide(s) and in the prophylaxis against second determined pathological condition(s) in the same mammalian host by eliciting a T cell memory immune response against a second group of epitopes contained in said polypeptide(s), said immune responses being obtained after administration of said vector-carried polypeptide(s) into said host, wherein said prophylaxis against second determined pathological condition(s) is not observed when said second group of epitopes is not contained in said administered vector-carried polypeptide(s). |
申请公布号 |
EP2478915(A1) |
申请公布日期 |
2012.07.25 |
申请号 |
EP20110305069 |
申请日期 |
2011.01.24 |
申请人 |
GENTICEL |
发明人 |
EQUERRE, MICHAEL;MOMOT, MARIE;GOUBIER, ANNE;MISSERI, YOLANDE |
分类号 |
A61K39/12;C07K14/025;C07K14/235 |
主分类号 |
A61K39/12 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|