发明名称 JNK modulators
摘要 Compounds of formula I modulate JNK: wherein X1 and X2 are each simultaneously N or CH; X3 is CH—R2 or N—SO2R, where R is lower alkyl; R1 is aryl or heteroaryl, substituted with 0-3 lower alkyl radicals; R2 is where R3 is H, lower acyl, or an amino acid, or a pharmaceutically acceptable salt thereof.
申请公布号 US8227478(B2) 申请公布日期 2012.07.24
申请号 US20090635076 申请日期 2009.12.10
申请人 GONG LEYI;JAHANGIR ALAM;REUTER DEBORAH CAROL;ROCHE PALO ALTO LLC 发明人 GONG LEYI;JAHANGIR ALAM;REUTER DEBORAH CAROL
分类号 C07D403/14;A61K31/506 主分类号 C07D403/14
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