发明名称 |
Methods for identifying kremen polypeptide binding partners |
摘要 |
The present invention relates to a composition useful for the diagnosis and therapy of diseases associated with aberrant expression of the gene encoding the receptor Kremen 1 and/or Kremen 2 e.g. tumors or diseases of the kidneys, bones and eyes, lipid and glucose metabolism and obesity. The present invention also relates to a pharmaceutical composition containing a compound which is capable of modifying (a) the expression of the gene encoding Kremen 1 and/or Kremen 2 or (b) the activity of the Kremen 1 and/or Kremen 2 receptor.
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申请公布号 |
US8227200(B2) |
申请公布日期 |
2012.07.24 |
申请号 |
US201113066024 |
申请日期 |
2011.04.05 |
申请人 |
NIEHRS CHRISTOF;MAO BINGYU;DEUTSCHES KREBSFORSCHUNGSZENTRUM STIFTUNG DES OFFENTLICHEN RECHTS |
发明人 |
NIEHRS CHRISTOF;MAO BINGYU |
分类号 |
G01N33/53;A61K31/7088;A61K38/00;A61K38/17;A61K39/395;A61K45/00;A61K48/00;A61P3/00;A61P3/04;A61P3/06;A61P3/10;A61P13/12;A61P19/00;A61P19/08;A61P27/02;A61P35/00;A61P43/00;C07K14/705;C07K16/28;C12N15/09;C12Q1/02;C12Q1/68;G01N33/15;G01N33/50;G01N33/566;G01N33/574;G01N37/00 |
主分类号 |
G01N33/53 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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