| 发明名称 |
Recombinant anti-VLA4 antibody molecules |
| 摘要 |
The present invention disclosed recombinant anti-VLA-4 antibody molecules, including humanized recombinant anti-VLA-4 antibody molecules. These antibodies are useful in the treatment of specific and non-specific inflammation, including asthma and inflammatory bowel disease. In addition, the humanized recombinant anti-VLA-4 antibodies disclosed can be useful in methods of diagnosing and localizing sites of inflammation. |
| 申请公布号 |
US8226950(B2) |
申请公布日期 |
2012.07.24 |
| 申请号 |
US20100891284 |
申请日期 |
2010.09.27 |
| 申请人 |
LOBB ROY R.;CARR FRANK J.;TEMPEST PHILIP R.;BIOGEN IDEC MA INC. |
发明人 |
LOBB ROY R.;CARR FRANK J.;TEMPEST PHILIP R. |
| 分类号 |
A61K39/395;C12N15/09;A61K38/00;A61P7/02;A61P9/10;A61P11/00;A61P11/06;A61P29/00;A61P31/00;A61P35/00;A61P35/02;A61P37/02;C07K14/78;C07K16/18;C07K16/28;C07K19/00;C12N1/15;C12N1/19;C12N1/21;C12N5/00;C12N5/10;C12N15/13;C12P21/02;C12P21/08;C12R1/91;G01N33/53;G01N33/577 |
主分类号 |
A61K39/395 |
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