发明名称 |
Method of preparing a taste-masking oral dosage form |
摘要 |
A method of preparing a taste-masking oral dosage form is provided. The method includes providing a first solution comprising a pharmaceutically active ingredient and a starch, providing a second solution comprising a hydrophilic polymer and a surfactant, blending the first and second solution to form a plurality of microparticles by a granulating process, wherein the microparticle is a co-crystal structure comprising the pharmaceutically active ingredient and the starch, and performing a compression-molding process to form the tablet. |
申请公布号 |
US8226981(B2) |
申请公布日期 |
2012.07.24 |
申请号 |
US20070896753 |
申请日期 |
2007.09.05 |
申请人 |
YANG CHIH-CHIANG;WANG WEN-CHE;CHEN HUI-YU;MEDICAL AND PHARMACEUTICAL INDUSTRY TECHNOLOGY AND DEVELOPMENT CENTER |
发明人 |
YANG CHIH-CHIANG;WANG WEN-CHE;CHEN HUI-YU |
分类号 |
A61K9/20;A61K9/16;A61K9/26;A61K9/46;A61K31/717 |
主分类号 |
A61K9/20 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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