NOVEL AMIDE DERIVATIVE FOR INHIBITING THE GROWTH OF CANCER CELLS
摘要
The present invention provides a novel amide derivative of formula (I): (see formula I) and a pharmaceutically acceptable salt thereof which selectively and effectively inhibits the growth of cancer cells induced by the overexpression of an epidermal growth factor receptor and also prevents the development of drug resistance caused by the mutation of EGFR tyrosine kinase, and a pharmaceutical composition comprising same as an active ingredient.
申请公布号
CA2687180(C)
申请公布日期
2012.07.24
申请号
CA20082687180
申请日期
2008.06.05
申请人
HANMI PHARM. CO., LTD.
发明人
LEE, KWANG-OK;CHA, MI YOUNG;KIM, MI RA;JUNG, YOUNG HEE;LEE, CHANG GON;KIM, SE YOUNG;BANG, KEUKCHAN;PARK, BUM WOO;CHOI, BO IM;CHAE, YUN JUNG;KO, MI YOUNG;KIM, HAN KYONG;AHN, YOUNG-GIL;KIM, MAENG SUP;LEE, GWAN SUN